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Students measure the oxygen consumption of mitochondrial extracts in the presence of different substrates, inhibitors, and ADP to investigate the TCA cycle, electron transport, and oxidative phosphorylation. Seven substrates and six inhibitors can be used in any order or combination by the student, providing the flexibility for a number of different experiments.

Discipline: cell biology
Topic: TCA cycle, electron transport, oxidative phosphorylation
Product: Biology Labs On-Line
Vendor: Pearson Higher Education
Technical requirements: Java
Accessibility info: Pearson Accessibility Statement
Link to Lab: MitochondriaLab
Reviews: none
MERLOT Resources: personal collections
Instructional materials: instructor and lab manuals available online from vendor
Description: Series of interactive, inquiry-based simulations and exercises designed for college level biology students.
Case studies: none available